JOURNAL OF INTELLIGENT SYSTEMS WITH APPLICATIONS

Year: 2025, Volume: 8, Number: 2
Published : Jan 18, 2026

Development of Implants to Prevent Pancreatic Fistula and Evaluation of the Effects of Computational Fluid Dynamics

Ahmet Emir Öğüt (1), Samet Çıklaçandır (2)

(1) Dept. of Biomedical Engineering, Izmir Katip Celebi University, Izmir
(2) Dept. of Biomedical Engineering, Izmir Katip Celebi University, Izmir
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Abstract

The Whipple procedure is a complex surgery in which the head of the pancreas, a part of the duodenum, the gallbladder, and a portion of the stomach are removed. This procedure is performed to remove the tumor and preserve the healthy structure. One of the potential risks and the most common one is the postoperative pancreatic fistula (POPF), which is caused by the pancreatic fluid leakage from the anastomotic sutures. This study aims to develop an implant for reducing the leakage and the suture needs. Furthermore, the design is supported with computational fluid dynamics (CFD) analysis to evaluate the pancreatic fluid flow behavior.

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